Metabolomics to Exploit the Primed Immune System of Tomato Fruit.
Identifieur interne : 000127 ( Main/Exploration ); précédent : 000126; suivant : 000128Metabolomics to Exploit the Primed Immune System of Tomato Fruit.
Auteurs : Estrella Luna [Royaume-Uni] ; Amélie Flandin [France] ; Cédric Cassan [France] ; Sylvain Prigent [France] ; Chloé Chevanne [France] ; Camélia Feyrouse Kadiri [France] ; Yves Gibon [France] ; Pierre Pétriacq [France]Source :
- Metabolites [ 2218-1989 ] ; 2020.
Abstract
Tomato is a major crop suffering substantial yield losses from diseases, as fruit decay at a postharvest level can claim up to 50% of the total production worldwide. Due to the environmental risks of fungicides, there is an increasing interest in exploiting plant immunity through priming, which is an adaptive strategy that improves plant defensive capacity by stimulating induced mechanisms. Broad-spectrum defence priming can be triggered by the compound ß-aminobutyric acid (BABA). In tomato plants, BABA induces resistance against various fungal and bacterial pathogens and different methods of application result in durable protection. Here, we demonstrate that the treatment of tomato plants with BABA resulted in a durable induced resistance in tomato fruit against Botrytiscinerea, Phytophthorainfestans and Pseudomonassyringae. Targeted and untargeted metabolomics were used to investigate the metabolic regulations that underpin the priming of tomato fruit against pathogenic microbes that present different infection strategies. Metabolomic analyses revealed major changes after BABA treatment and after inoculation. Remarkably, primed responses seemed specific to the type of infection, rather than showing a common fingerprint of BABA-induced priming. Furthermore, top-down modelling from the detected metabolic markers allowed for the accurate prediction of the measured resistance to fruit pathogens and demonstrated that soluble sugars are essential to predict resistance to fruit pathogens. Altogether, our results demonstrate that metabolomics is particularly insightful for a better understanding of defence priming in fruit. Further experiments are underway in order to identify key metabolites that mediate broad-spectrum BABA-induced priming in tomato fruit.
DOI: 10.3390/metabo10030096
PubMed: 32155921
PubMed Central: PMC7143431
Affiliations:
Links toward previous steps (curation, corpus...)
Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Metabolomics to Exploit the Primed Immune System of Tomato Fruit.</title><author><name sortKey="Luna, Estrella" sort="Luna, Estrella" uniqKey="Luna E" first="Estrella" last="Luna">Estrella Luna</name><affiliation wicri:level="1"><nlm:affiliation>School of Biosciences, Uni. Birmingham, Birmingham B15 2TT, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>School of Biosciences, Uni. Birmingham, Birmingham B15 2TT</wicri:regionArea><wicri:noRegion>Birmingham B15 2TT</wicri:noRegion></affiliation></author><author><name sortKey="Flandin, Amelie" sort="Flandin, Amelie" uniqKey="Flandin A" first="Amélie" last="Flandin">Amélie Flandin</name><affiliation wicri:level="3"><nlm:affiliation>UMR BFP, University Bordeaux, INRAE, 33882 Villenave d'Ornon, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>UMR BFP, University Bordeaux, INRAE, 33882 Villenave d'Ornon</wicri:regionArea><placeName><region type="region" nuts="2">Nouvelle-Aquitaine</region><region type="old region" nuts="2">Aquitaine</region><settlement type="city">Villenave d'Ornon</settlement></placeName></affiliation><affiliation wicri:level="3"><nlm:affiliation>Bordeaux Metabolome, MetaboHUB, PHENOME-EMPHASIS, 33140 Villenave d'Ornon, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Bordeaux Metabolome, MetaboHUB, PHENOME-EMPHASIS, 33140 Villenave d'Ornon</wicri:regionArea><placeName><region type="region" nuts="2">Nouvelle-Aquitaine</region><region type="old region" nuts="2">Aquitaine</region><settlement type="city">Villenave d'Ornon</settlement></placeName></affiliation></author><author><name sortKey="Cassan, Cedric" sort="Cassan, Cedric" uniqKey="Cassan C" first="Cédric" last="Cassan">Cédric Cassan</name><affiliation wicri:level="3"><nlm:affiliation>UMR BFP, University Bordeaux, INRAE, 33882 Villenave d'Ornon, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>UMR BFP, University Bordeaux, INRAE, 33882 Villenave d'Ornon</wicri:regionArea><placeName><region type="region" nuts="2">Nouvelle-Aquitaine</region><region type="old region" nuts="2">Aquitaine</region><settlement type="city">Villenave d'Ornon</settlement></placeName></affiliation><affiliation wicri:level="3"><nlm:affiliation>Bordeaux Metabolome, MetaboHUB, PHENOME-EMPHASIS, 33140 Villenave d'Ornon, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Bordeaux Metabolome, MetaboHUB, PHENOME-EMPHASIS, 33140 Villenave d'Ornon</wicri:regionArea><placeName><region type="region" nuts="2">Nouvelle-Aquitaine</region><region type="old region" nuts="2">Aquitaine</region><settlement type="city">Villenave d'Ornon</settlement></placeName></affiliation></author><author><name sortKey="Prigent, Sylvain" sort="Prigent, Sylvain" uniqKey="Prigent S" first="Sylvain" last="Prigent">Sylvain Prigent</name><affiliation wicri:level="3"><nlm:affiliation>UMR BFP, University Bordeaux, INRAE, 33882 Villenave d'Ornon, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>UMR BFP, University Bordeaux, INRAE, 33882 Villenave d'Ornon</wicri:regionArea><placeName><region type="region" nuts="2">Nouvelle-Aquitaine</region><region type="old region" nuts="2">Aquitaine</region><settlement type="city">Villenave d'Ornon</settlement></placeName></affiliation><affiliation wicri:level="3"><nlm:affiliation>Bordeaux Metabolome, MetaboHUB, PHENOME-EMPHASIS, 33140 Villenave d'Ornon, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Bordeaux Metabolome, MetaboHUB, PHENOME-EMPHASIS, 33140 Villenave d'Ornon</wicri:regionArea><placeName><region type="region" nuts="2">Nouvelle-Aquitaine</region><region type="old region" nuts="2">Aquitaine</region><settlement type="city">Villenave d'Ornon</settlement></placeName></affiliation></author><author><name sortKey="Chevanne, Chloe" sort="Chevanne, Chloe" uniqKey="Chevanne C" first="Chloé" last="Chevanne">Chloé Chevanne</name><affiliation wicri:level="3"><nlm:affiliation>UMR BFP, University Bordeaux, INRAE, 33882 Villenave d'Ornon, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>UMR BFP, University Bordeaux, INRAE, 33882 Villenave d'Ornon</wicri:regionArea><placeName><region type="region" nuts="2">Nouvelle-Aquitaine</region><region type="old region" nuts="2">Aquitaine</region><settlement type="city">Villenave d'Ornon</settlement></placeName></affiliation></author><author><name sortKey="Kadiri, Camelia Feyrouse" sort="Kadiri, Camelia Feyrouse" uniqKey="Kadiri C" first="Camélia Feyrouse" last="Kadiri">Camélia Feyrouse Kadiri</name><affiliation wicri:level="3"><nlm:affiliation>UMR BFP, University Bordeaux, INRAE, 33882 Villenave d'Ornon, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>UMR BFP, University Bordeaux, INRAE, 33882 Villenave d'Ornon</wicri:regionArea><placeName><region type="region" nuts="2">Nouvelle-Aquitaine</region><region type="old region" nuts="2">Aquitaine</region><settlement type="city">Villenave d'Ornon</settlement></placeName></affiliation></author><author><name sortKey="Gibon, Yves" sort="Gibon, Yves" uniqKey="Gibon Y" first="Yves" last="Gibon">Yves Gibon</name><affiliation wicri:level="3"><nlm:affiliation>UMR BFP, University Bordeaux, INRAE, 33882 Villenave d'Ornon, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>UMR BFP, University Bordeaux, INRAE, 33882 Villenave d'Ornon</wicri:regionArea><placeName><region type="region" nuts="2">Nouvelle-Aquitaine</region><region type="old region" nuts="2">Aquitaine</region><settlement type="city">Villenave d'Ornon</settlement></placeName></affiliation><affiliation wicri:level="3"><nlm:affiliation>Bordeaux Metabolome, MetaboHUB, PHENOME-EMPHASIS, 33140 Villenave d'Ornon, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Bordeaux Metabolome, MetaboHUB, PHENOME-EMPHASIS, 33140 Villenave d'Ornon</wicri:regionArea><placeName><region type="region" nuts="2">Nouvelle-Aquitaine</region><region type="old region" nuts="2">Aquitaine</region><settlement type="city">Villenave d'Ornon</settlement></placeName></affiliation></author><author><name sortKey="Petriacq, Pierre" sort="Petriacq, Pierre" uniqKey="Petriacq P" first="Pierre" last="Pétriacq">Pierre Pétriacq</name><affiliation wicri:level="3"><nlm:affiliation>UMR BFP, University Bordeaux, INRAE, 33882 Villenave d'Ornon, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>UMR BFP, University Bordeaux, INRAE, 33882 Villenave d'Ornon</wicri:regionArea><placeName><region type="region" nuts="2">Nouvelle-Aquitaine</region><region type="old region" nuts="2">Aquitaine</region><settlement type="city">Villenave d'Ornon</settlement></placeName></affiliation><affiliation wicri:level="3"><nlm:affiliation>Bordeaux Metabolome, MetaboHUB, PHENOME-EMPHASIS, 33140 Villenave d'Ornon, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Bordeaux Metabolome, MetaboHUB, PHENOME-EMPHASIS, 33140 Villenave d'Ornon</wicri:regionArea><placeName><region type="region" nuts="2">Nouvelle-Aquitaine</region><region type="old region" nuts="2">Aquitaine</region><settlement type="city">Villenave d'Ornon</settlement></placeName></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2020">2020</date><idno type="RBID">pubmed:32155921</idno><idno type="pmid">32155921</idno><idno type="doi">10.3390/metabo10030096</idno><idno type="pmc">PMC7143431</idno><idno type="wicri:Area/Main/Corpus">000250</idno><idno type="wicri:explorRef" wicri:stream="Main" wicri:step="Corpus" wicri:corpus="PubMed">000250</idno><idno type="wicri:Area/Main/Curation">000250</idno><idno type="wicri:explorRef" wicri:stream="Main" wicri:step="Curation">000250</idno><idno type="wicri:Area/Main/Exploration">000250</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Metabolomics to Exploit the Primed Immune System of Tomato Fruit.</title><author><name sortKey="Luna, Estrella" sort="Luna, Estrella" uniqKey="Luna E" first="Estrella" last="Luna">Estrella Luna</name><affiliation wicri:level="1"><nlm:affiliation>School of Biosciences, Uni. Birmingham, Birmingham B15 2TT, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>School of Biosciences, Uni. Birmingham, Birmingham B15 2TT</wicri:regionArea><wicri:noRegion>Birmingham B15 2TT</wicri:noRegion></affiliation></author><author><name sortKey="Flandin, Amelie" sort="Flandin, Amelie" uniqKey="Flandin A" first="Amélie" last="Flandin">Amélie Flandin</name><affiliation wicri:level="3"><nlm:affiliation>UMR BFP, University Bordeaux, INRAE, 33882 Villenave d'Ornon, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>UMR BFP, University Bordeaux, INRAE, 33882 Villenave d'Ornon</wicri:regionArea><placeName><region type="region" nuts="2">Nouvelle-Aquitaine</region><region type="old region" nuts="2">Aquitaine</region><settlement type="city">Villenave d'Ornon</settlement></placeName></affiliation><affiliation wicri:level="3"><nlm:affiliation>Bordeaux Metabolome, MetaboHUB, PHENOME-EMPHASIS, 33140 Villenave d'Ornon, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Bordeaux Metabolome, MetaboHUB, PHENOME-EMPHASIS, 33140 Villenave d'Ornon</wicri:regionArea><placeName><region type="region" nuts="2">Nouvelle-Aquitaine</region><region type="old region" nuts="2">Aquitaine</region><settlement type="city">Villenave d'Ornon</settlement></placeName></affiliation></author><author><name sortKey="Cassan, Cedric" sort="Cassan, Cedric" uniqKey="Cassan C" first="Cédric" last="Cassan">Cédric Cassan</name><affiliation wicri:level="3"><nlm:affiliation>UMR BFP, University Bordeaux, INRAE, 33882 Villenave d'Ornon, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>UMR BFP, University Bordeaux, INRAE, 33882 Villenave d'Ornon</wicri:regionArea><placeName><region type="region" nuts="2">Nouvelle-Aquitaine</region><region type="old region" nuts="2">Aquitaine</region><settlement type="city">Villenave d'Ornon</settlement></placeName></affiliation><affiliation wicri:level="3"><nlm:affiliation>Bordeaux Metabolome, MetaboHUB, PHENOME-EMPHASIS, 33140 Villenave d'Ornon, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Bordeaux Metabolome, MetaboHUB, PHENOME-EMPHASIS, 33140 Villenave d'Ornon</wicri:regionArea><placeName><region type="region" nuts="2">Nouvelle-Aquitaine</region><region type="old region" nuts="2">Aquitaine</region><settlement type="city">Villenave d'Ornon</settlement></placeName></affiliation></author><author><name sortKey="Prigent, Sylvain" sort="Prigent, Sylvain" uniqKey="Prigent S" first="Sylvain" last="Prigent">Sylvain Prigent</name><affiliation wicri:level="3"><nlm:affiliation>UMR BFP, University Bordeaux, INRAE, 33882 Villenave d'Ornon, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>UMR BFP, University Bordeaux, INRAE, 33882 Villenave d'Ornon</wicri:regionArea><placeName><region type="region" nuts="2">Nouvelle-Aquitaine</region><region type="old region" nuts="2">Aquitaine</region><settlement type="city">Villenave d'Ornon</settlement></placeName></affiliation><affiliation wicri:level="3"><nlm:affiliation>Bordeaux Metabolome, MetaboHUB, PHENOME-EMPHASIS, 33140 Villenave d'Ornon, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Bordeaux Metabolome, MetaboHUB, PHENOME-EMPHASIS, 33140 Villenave d'Ornon</wicri:regionArea><placeName><region type="region" nuts="2">Nouvelle-Aquitaine</region><region type="old region" nuts="2">Aquitaine</region><settlement type="city">Villenave d'Ornon</settlement></placeName></affiliation></author><author><name sortKey="Chevanne, Chloe" sort="Chevanne, Chloe" uniqKey="Chevanne C" first="Chloé" last="Chevanne">Chloé Chevanne</name><affiliation wicri:level="3"><nlm:affiliation>UMR BFP, University Bordeaux, INRAE, 33882 Villenave d'Ornon, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>UMR BFP, University Bordeaux, INRAE, 33882 Villenave d'Ornon</wicri:regionArea><placeName><region type="region" nuts="2">Nouvelle-Aquitaine</region><region type="old region" nuts="2">Aquitaine</region><settlement type="city">Villenave d'Ornon</settlement></placeName></affiliation></author><author><name sortKey="Kadiri, Camelia Feyrouse" sort="Kadiri, Camelia Feyrouse" uniqKey="Kadiri C" first="Camélia Feyrouse" last="Kadiri">Camélia Feyrouse Kadiri</name><affiliation wicri:level="3"><nlm:affiliation>UMR BFP, University Bordeaux, INRAE, 33882 Villenave d'Ornon, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>UMR BFP, University Bordeaux, INRAE, 33882 Villenave d'Ornon</wicri:regionArea><placeName><region type="region" nuts="2">Nouvelle-Aquitaine</region><region type="old region" nuts="2">Aquitaine</region><settlement type="city">Villenave d'Ornon</settlement></placeName></affiliation></author><author><name sortKey="Gibon, Yves" sort="Gibon, Yves" uniqKey="Gibon Y" first="Yves" last="Gibon">Yves Gibon</name><affiliation wicri:level="3"><nlm:affiliation>UMR BFP, University Bordeaux, INRAE, 33882 Villenave d'Ornon, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>UMR BFP, University Bordeaux, INRAE, 33882 Villenave d'Ornon</wicri:regionArea><placeName><region type="region" nuts="2">Nouvelle-Aquitaine</region><region type="old region" nuts="2">Aquitaine</region><settlement type="city">Villenave d'Ornon</settlement></placeName></affiliation><affiliation wicri:level="3"><nlm:affiliation>Bordeaux Metabolome, MetaboHUB, PHENOME-EMPHASIS, 33140 Villenave d'Ornon, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Bordeaux Metabolome, MetaboHUB, PHENOME-EMPHASIS, 33140 Villenave d'Ornon</wicri:regionArea><placeName><region type="region" nuts="2">Nouvelle-Aquitaine</region><region type="old region" nuts="2">Aquitaine</region><settlement type="city">Villenave d'Ornon</settlement></placeName></affiliation></author><author><name sortKey="Petriacq, Pierre" sort="Petriacq, Pierre" uniqKey="Petriacq P" first="Pierre" last="Pétriacq">Pierre Pétriacq</name><affiliation wicri:level="3"><nlm:affiliation>UMR BFP, University Bordeaux, INRAE, 33882 Villenave d'Ornon, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>UMR BFP, University Bordeaux, INRAE, 33882 Villenave d'Ornon</wicri:regionArea><placeName><region type="region" nuts="2">Nouvelle-Aquitaine</region><region type="old region" nuts="2">Aquitaine</region><settlement type="city">Villenave d'Ornon</settlement></placeName></affiliation><affiliation wicri:level="3"><nlm:affiliation>Bordeaux Metabolome, MetaboHUB, PHENOME-EMPHASIS, 33140 Villenave d'Ornon, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Bordeaux Metabolome, MetaboHUB, PHENOME-EMPHASIS, 33140 Villenave d'Ornon</wicri:regionArea><placeName><region type="region" nuts="2">Nouvelle-Aquitaine</region><region type="old region" nuts="2">Aquitaine</region><settlement type="city">Villenave d'Ornon</settlement></placeName></affiliation></author></analytic><series><title level="j">Metabolites</title><idno type="ISSN">2218-1989</idno><imprint><date when="2020" type="published">2020</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Tomato is a major crop suffering substantial yield losses from diseases, as fruit decay at a postharvest level can claim up to 50% of the total production worldwide. Due to the environmental risks of fungicides, there is an increasing interest in exploiting plant immunity through priming, which is an adaptive strategy that improves plant defensive capacity by stimulating induced mechanisms. Broad-spectrum defence priming can be triggered by the compound ß-aminobutyric acid (BABA). In tomato plants, BABA induces resistance against various fungal and bacterial pathogens and different methods of application result in durable protection. Here, we demonstrate that the treatment of tomato plants with BABA resulted in a durable induced resistance in tomato fruit against <i>Botrytis</i><i>cinerea</i>, <i>Phytophthora</i><i>infestans</i> and <i>Pseudomonas</i><i>syringae</i>. Targeted and untargeted metabolomics were used to investigate the metabolic regulations that underpin the priming of tomato fruit against pathogenic microbes that present different infection strategies. Metabolomic analyses revealed major changes after BABA treatment and after inoculation. Remarkably, primed responses seemed specific to the type of infection, rather than showing a common fingerprint of BABA-induced priming. Furthermore, top-down modelling from the detected metabolic markers allowed for the accurate prediction of the measured resistance to fruit pathogens and demonstrated that soluble sugars are essential to predict resistance to fruit pathogens. Altogether, our results demonstrate that metabolomics is particularly insightful for a better understanding of defence priming in fruit. Further experiments are underway in order to identify key metabolites that mediate broad-spectrum BABA-induced priming in tomato fruit.</div></front></TEI><pubmed><MedlineCitation Status="PubMed-not-MEDLINE" Owner="NLM"><PMID Version="1">32155921</PMID><DateRevised><Year>2020</Year><Month>09</Month><Day>28</Day></DateRevised><Article PubModel="Electronic"><Journal><ISSN IssnType="Print">2218-1989</ISSN><JournalIssue CitedMedium="Print"><Volume>10</Volume><Issue>3</Issue><PubDate><Year>2020</Year><Month>Mar</Month><Day>06</Day></PubDate></JournalIssue><Title>Metabolites</Title><ISOAbbreviation>Metabolites</ISOAbbreviation></Journal><ArticleTitle>Metabolomics to Exploit the Primed Immune System of Tomato Fruit.</ArticleTitle><ELocationID EIdType="pii" ValidYN="Y">E96</ELocationID><ELocationID EIdType="doi" ValidYN="Y">10.3390/metabo10030096</ELocationID><Abstract><AbstractText>Tomato is a major crop suffering substantial yield losses from diseases, as fruit decay at a postharvest level can claim up to 50% of the total production worldwide. Due to the environmental risks of fungicides, there is an increasing interest in exploiting plant immunity through priming, which is an adaptive strategy that improves plant defensive capacity by stimulating induced mechanisms. Broad-spectrum defence priming can be triggered by the compound ß-aminobutyric acid (BABA). In tomato plants, BABA induces resistance against various fungal and bacterial pathogens and different methods of application result in durable protection. Here, we demonstrate that the treatment of tomato plants with BABA resulted in a durable induced resistance in tomato fruit against <i>Botrytis</i><i>cinerea</i>, <i>Phytophthora</i><i>infestans</i> and <i>Pseudomonas</i><i>syringae</i>. Targeted and untargeted metabolomics were used to investigate the metabolic regulations that underpin the priming of tomato fruit against pathogenic microbes that present different infection strategies. Metabolomic analyses revealed major changes after BABA treatment and after inoculation. Remarkably, primed responses seemed specific to the type of infection, rather than showing a common fingerprint of BABA-induced priming. Furthermore, top-down modelling from the detected metabolic markers allowed for the accurate prediction of the measured resistance to fruit pathogens and demonstrated that soluble sugars are essential to predict resistance to fruit pathogens. Altogether, our results demonstrate that metabolomics is particularly insightful for a better understanding of defence priming in fruit. Further experiments are underway in order to identify key metabolites that mediate broad-spectrum BABA-induced priming in tomato fruit.</AbstractText></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Luna</LastName><ForeName>Estrella</ForeName><Initials>E</Initials><AffiliationInfo><Affiliation>School of Biosciences, Uni. Birmingham, Birmingham B15 2TT, UK.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Flandin</LastName><ForeName>Amélie</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>UMR BFP, University Bordeaux, INRAE, 33882 Villenave d'Ornon, France.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Bordeaux Metabolome, MetaboHUB, PHENOME-EMPHASIS, 33140 Villenave d'Ornon, France.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Cassan</LastName><ForeName>Cédric</ForeName><Initials>C</Initials><AffiliationInfo><Affiliation>UMR BFP, University Bordeaux, INRAE, 33882 Villenave d'Ornon, France.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Bordeaux Metabolome, MetaboHUB, PHENOME-EMPHASIS, 33140 Villenave d'Ornon, France.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Prigent</LastName><ForeName>Sylvain</ForeName><Initials>S</Initials><AffiliationInfo><Affiliation>UMR BFP, University Bordeaux, INRAE, 33882 Villenave d'Ornon, France.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Bordeaux Metabolome, MetaboHUB, PHENOME-EMPHASIS, 33140 Villenave d'Ornon, France.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Chevanne</LastName><ForeName>Chloé</ForeName><Initials>C</Initials><AffiliationInfo><Affiliation>UMR BFP, University Bordeaux, INRAE, 33882 Villenave d'Ornon, France.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Kadiri</LastName><ForeName>Camélia Feyrouse</ForeName><Initials>CF</Initials><AffiliationInfo><Affiliation>UMR BFP, University Bordeaux, INRAE, 33882 Villenave d'Ornon, France.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Gibon</LastName><ForeName>Yves</ForeName><Initials>Y</Initials><AffiliationInfo><Affiliation>UMR BFP, University Bordeaux, INRAE, 33882 Villenave d'Ornon, France.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Bordeaux Metabolome, MetaboHUB, PHENOME-EMPHASIS, 33140 Villenave d'Ornon, France.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Pétriacq</LastName><ForeName>Pierre</ForeName><Initials>P</Initials><AffiliationInfo><Affiliation>UMR BFP, University Bordeaux, INRAE, 33882 Villenave d'Ornon, France.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Bordeaux Metabolome, MetaboHUB, PHENOME-EMPHASIS, 33140 Villenave d'Ornon, France.</Affiliation></AffiliationInfo></Author></AuthorList><Language>eng</Language><GrantList CompleteYN="Y"><Grant><GrantID>ANR-11-INBS-0010</GrantID><Agency>MetaboHUB</Agency><Country></Country></Grant><Grant><GrantID>ANR-11-INBS-0012</GrantID><Agency>PHENOME</Agency><Country></Country></Grant><Grant><GrantID>BB/P00556X/1</GrantID><Agency>BBSRC Future Leader Fellowship</Agency><Country></Country></Grant><Grant><GrantID>BB/P00556X/2</GrantID><Agency>BBSRC Future Leader Fellowship</Agency><Country></Country></Grant></GrantList><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType></PublicationTypeList><ArticleDate DateType="Electronic"><Year>2020</Year><Month>03</Month><Day>06</Day></ArticleDate></Article><MedlineJournalInfo><Country>Switzerland</Country><MedlineTA>Metabolites</MedlineTA><NlmUniqueID>101578790</NlmUniqueID><ISSNLinking>2218-1989</ISSNLinking></MedlineJournalInfo><KeywordList Owner="NOTNLM"><Keyword MajorTopicYN="N">BABA</Keyword><Keyword MajorTopicYN="N">Botrytis cinerea</Keyword><Keyword MajorTopicYN="N">Phytophthora infestans</Keyword><Keyword MajorTopicYN="N">Pseudomonas syringae</Keyword><Keyword MajorTopicYN="N">biochemical phenotyping</Keyword><Keyword MajorTopicYN="N">metabolomics</Keyword><Keyword MajorTopicYN="N">priming</Keyword><Keyword MajorTopicYN="N">tomato</Keyword></KeywordList><CoiStatement>The authors declare no conflict of interest.</CoiStatement></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="received"><Year>2020</Year><Month>02</Month><Day>14</Day></PubMedPubDate><PubMedPubDate PubStatus="revised"><Year>2020</Year><Month>03</Month><Day>03</Day></PubMedPubDate><PubMedPubDate PubStatus="accepted"><Year>2020</Year><Month>03</Month><Day>03</Day></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>2020</Year><Month>3</Month><Day>12</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="pubmed"><Year>2020</Year><Month>3</Month><Day>12</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2020</Year><Month>3</Month><Day>12</Day><Hour>6</Hour><Minute>1</Minute></PubMedPubDate></History><PublicationStatus>epublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">32155921</ArticleId><ArticleId IdType="pii">metabo10030096</ArticleId><ArticleId IdType="doi">10.3390/metabo10030096</ArticleId><ArticleId IdType="pmc">PMC7143431</ArticleId></ArticleIdList><ReferenceList><Reference><Citation>Mol Plant Pathol. 2008 May;9(3):385-402</Citation><ArticleIdList><ArticleId IdType="pubmed">18705878</ArticleId></ArticleIdList></Reference><Reference><Citation>J Stat Softw. 2010;33(1):1-22</Citation><ArticleIdList><ArticleId IdType="pubmed">20808728</ArticleId></ArticleIdList></Reference><Reference><Citation>Proc Natl Acad Sci U S A. 2000 Nov 7;97(23):12920-5</Citation><ArticleIdList><ArticleId IdType="pubmed">11058166</ArticleId></ArticleIdList></Reference><Reference><Citation>Anal Biochem. 1976 May 7;72:248-54</Citation><ArticleIdList><ArticleId IdType="pubmed">942051</ArticleId></ArticleIdList></Reference><Reference><Citation>Ther Drug Monit. 2005 Dec;27(6):747-51</Citation><ArticleIdList><ArticleId IdType="pubmed">16404815</ArticleId></ArticleIdList></Reference><Reference><Citation>Plant J. 2015 Mar;81(5):822-35</Citation><ArticleIdList><ArticleId IdType="pubmed">25600836</ArticleId></ArticleIdList></Reference><Reference><Citation>Biotechniques. 2003 Feb;34(2):374-8</Citation><ArticleIdList><ArticleId IdType="pubmed">12613259</ArticleId></ArticleIdList></Reference><Reference><Citation>New Phytol. 2017 Jan;213(2):552-559</Citation><ArticleIdList><ArticleId IdType="pubmed">27782340</ArticleId></ArticleIdList></Reference><Reference><Citation>New Phytol. 2017 Mar;213(4):1726-1739</Citation><ArticleIdList><ArticleId IdType="pubmed">27861943</ArticleId></ArticleIdList></Reference><Reference><Citation>Plant Cell Physiol. 2012 Feb;53(2):e1</Citation><ArticleIdList><ArticleId IdType="pubmed">22123792</ArticleId></ArticleIdList></Reference><Reference><Citation>Agric Syst. 2017 Jul;155:213-224</Citation><ArticleIdList><ArticleId IdType="pubmed">28701814</ArticleId></ArticleIdList></Reference><Reference><Citation>Annu Rev Plant Biol. 2017 Apr 28;68:485-512</Citation><ArticleIdList><ArticleId IdType="pubmed">28226238</ArticleId></ArticleIdList></Reference><Reference><Citation>Nucleic Acids Res. 2015 Jul 1;43(W1):W251-7</Citation><ArticleIdList><ArticleId IdType="pubmed">25897128</ArticleId></ArticleIdList></Reference><Reference><Citation>Plant Physiol. 2019 Jul;180(3):1709-1724</Citation><ArticleIdList><ArticleId IdType="pubmed">31015299</ArticleId></ArticleIdList></Reference><Reference><Citation>Plant Dis. 2016 Apr;100(4):704-710</Citation><ArticleIdList><ArticleId IdType="pubmed">30688613</ArticleId></ArticleIdList></Reference><Reference><Citation>Trends Plant Sci. 2016 Oct;21(10):818-822</Citation><ArticleIdList><ArticleId IdType="pubmed">27507609</ArticleId></ArticleIdList></Reference><Reference><Citation>Biol Rev Camb Philos Soc. 2016 Nov;91(4):1118-1133</Citation><ArticleIdList><ArticleId IdType="pubmed">26289992</ArticleId></ArticleIdList></Reference><Reference><Citation>J Biomed Biotechnol. 2012;2012:263910</Citation><ArticleIdList><ArticleId IdType="pubmed">22550397</ArticleId></ArticleIdList></Reference><Reference><Citation>Anal Chem. 2006 Feb 1;78(3):779-87</Citation><ArticleIdList><ArticleId IdType="pubmed">16448051</ArticleId></ArticleIdList></Reference><Reference><Citation>Plants (Basel). 2018 Sep 21;7(4):</Citation><ArticleIdList><ArticleId IdType="pubmed">30248893</ArticleId></ArticleIdList></Reference><Reference><Citation>Plant Physiol. 2014 Mar;164(3):1204-21</Citation><ArticleIdList><ArticleId IdType="pubmed">24474652</ArticleId></ArticleIdList></Reference><Reference><Citation>Trends Plant Sci. 2015 Jul;20(7):443-52</Citation><ArticleIdList><ArticleId IdType="pubmed">25921921</ArticleId></ArticleIdList></Reference><Reference><Citation>Plant Cell. 2014 Aug;26(8):3224-42</Citation><ArticleIdList><ArticleId IdType="pubmed">25139005</ArticleId></ArticleIdList></Reference><Reference><Citation>Mol Plant Pathol. 2012 Aug;13(6):614-29</Citation><ArticleIdList><ArticleId IdType="pubmed">22672649</ArticleId></ArticleIdList></Reference><Reference><Citation>New Phytol. 2012 Feb;193(3):770-8</Citation><ArticleIdList><ArticleId IdType="pubmed">22142268</ArticleId></ArticleIdList></Reference><Reference><Citation>Proc Natl Acad Sci U S A. 2006 Apr 4;103(14):5602-7</Citation><ArticleIdList><ArticleId IdType="pubmed">16565218</ArticleId></ArticleIdList></Reference><Reference><Citation>J Agric Food Chem. 2001 Nov;49(11):5315-21</Citation><ArticleIdList><ArticleId IdType="pubmed">11714322</ArticleId></ArticleIdList></Reference><Reference><Citation>Plant Signal Behav. 2014;9(5):e28916</Citation><ArticleIdList><ArticleId IdType="pubmed">24739434</ArticleId></ArticleIdList></Reference><Reference><Citation>Mol Plant Pathol. 2007 Sep;8(5):561-80</Citation><ArticleIdList><ArticleId IdType="pubmed">20507522</ArticleId></ArticleIdList></Reference><Reference><Citation>Nat Chem Biol. 2014 Jun;10(6):450-6</Citation><ArticleIdList><ArticleId IdType="pubmed">24776930</ArticleId></ArticleIdList></Reference><Reference><Citation>Ann Bot. 2017 Mar 1;119(5):931-943</Citation><ArticleIdList><ArticleId IdType="pubmed">28065923</ArticleId></ArticleIdList></Reference><Reference><Citation>Stat Med. 1990 Jul;9(7):811-8</Citation><ArticleIdList><ArticleId IdType="pubmed">2218183</ArticleId></ArticleIdList></Reference><Reference><Citation>Nature. 2007 Nov 1;450(7166):115-8</Citation><ArticleIdList><ArticleId IdType="pubmed">17914356</ArticleId></ArticleIdList></Reference><Reference><Citation>Front Plant Sci. 2019 Oct 11;10:1201</Citation><ArticleIdList><ArticleId IdType="pubmed">31681351</ArticleId></ArticleIdList></Reference><Reference><Citation>Plant Cell. 2005 Mar;17(3):987-99</Citation><ArticleIdList><ArticleId IdType="pubmed">15722464</ArticleId></ArticleIdList></Reference><Reference><Citation>BMC Genomics. 2018 Dec 11;19(Suppl 8):863</Citation><ArticleIdList><ArticleId IdType="pubmed">30537923</ArticleId></ArticleIdList></Reference><Reference><Citation>Plant J. 2017 Oct;92(1):147-162</Citation><ArticleIdList><ArticleId IdType="pubmed">28742258</ArticleId></ArticleIdList></Reference><Reference><Citation>Front Plant Sci. 2019 Jul 09;10:836</Citation><ArticleIdList><ArticleId IdType="pubmed">31354750</ArticleId></ArticleIdList></Reference><Reference><Citation>mBio. 2019 Jul 9;10(4):</Citation><ArticleIdList><ArticleId IdType="pubmed">31289172</ArticleId></ArticleIdList></Reference><Reference><Citation>Mol Plant Microbe Interact. 2014 Nov;27(11):1226-40</Citation><ArticleIdList><ArticleId IdType="pubmed">25025782</ArticleId></ArticleIdList></Reference><Reference><Citation>Theor Biol Med Model. 2009 Nov 12;6:24</Citation><ArticleIdList><ArticleId IdType="pubmed">19909526</ArticleId></ArticleIdList></Reference><Reference><Citation>Ann Bot. 2018 Jun 28;122(1):1-21</Citation><ArticleIdList><ArticleId IdType="pubmed">29718072</ArticleId></ArticleIdList></Reference><Reference><Citation>Nature. 2006 Nov 16;444(7117):323-9</Citation><ArticleIdList><ArticleId IdType="pubmed">17108957</ArticleId></ArticleIdList></Reference><Reference><Citation>Plant J. 2015 Jan;81(1):24-39</Citation><ArticleIdList><ArticleId IdType="pubmed">25279440</ArticleId></ArticleIdList></Reference><Reference><Citation>Plant Physiol. 2004 Jan;134(1):307-19</Citation><ArticleIdList><ArticleId IdType="pubmed">14684838</ArticleId></ArticleIdList></Reference><Reference><Citation>Plant J. 2002 Apr;30(2):221-35</Citation><ArticleIdList><ArticleId IdType="pubmed">12000458</ArticleId></ArticleIdList></Reference><Reference><Citation>Int J Mol Sci. 2018 Jun 13;19(6):</Citation><ArticleIdList><ArticleId IdType="pubmed">29899301</ArticleId></ArticleIdList></Reference></ReferenceList></PubmedData></pubmed><affiliations><list><country><li>France</li><li>Royaume-Uni</li></country><region><li>Aquitaine</li><li>Nouvelle-Aquitaine</li></region><settlement><li>Villenave d'Ornon</li></settlement></list><tree><country name="Royaume-Uni"><noRegion><name sortKey="Luna, Estrella" sort="Luna, Estrella" uniqKey="Luna E" first="Estrella" last="Luna">Estrella Luna</name></noRegion></country><country name="France"><region name="Nouvelle-Aquitaine"><name sortKey="Flandin, Amelie" sort="Flandin, Amelie" uniqKey="Flandin A" first="Amélie" last="Flandin">Amélie Flandin</name></region><name sortKey="Cassan, Cedric" sort="Cassan, Cedric" uniqKey="Cassan C" first="Cédric" last="Cassan">Cédric Cassan</name><name sortKey="Cassan, Cedric" sort="Cassan, Cedric" uniqKey="Cassan C" first="Cédric" last="Cassan">Cédric Cassan</name><name sortKey="Chevanne, Chloe" sort="Chevanne, Chloe" uniqKey="Chevanne C" first="Chloé" last="Chevanne">Chloé Chevanne</name><name sortKey="Flandin, Amelie" sort="Flandin, Amelie" uniqKey="Flandin A" first="Amélie" last="Flandin">Amélie Flandin</name><name sortKey="Gibon, Yves" sort="Gibon, Yves" uniqKey="Gibon Y" first="Yves" last="Gibon">Yves Gibon</name><name sortKey="Gibon, Yves" sort="Gibon, Yves" uniqKey="Gibon Y" first="Yves" last="Gibon">Yves Gibon</name><name sortKey="Kadiri, Camelia Feyrouse" sort="Kadiri, Camelia Feyrouse" uniqKey="Kadiri C" first="Camélia Feyrouse" last="Kadiri">Camélia Feyrouse Kadiri</name><name sortKey="Petriacq, Pierre" sort="Petriacq, Pierre" uniqKey="Petriacq P" first="Pierre" last="Pétriacq">Pierre Pétriacq</name><name sortKey="Petriacq, Pierre" sort="Petriacq, Pierre" uniqKey="Petriacq P" first="Pierre" last="Pétriacq">Pierre Pétriacq</name><name sortKey="Prigent, Sylvain" sort="Prigent, Sylvain" uniqKey="Prigent S" first="Sylvain" last="Prigent">Sylvain Prigent</name><name sortKey="Prigent, Sylvain" sort="Prigent, Sylvain" uniqKey="Prigent S" first="Sylvain" last="Prigent">Sylvain Prigent</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Bois/explor/PhytophthoraV1/Data/Main/Exploration
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000127 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 000127 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Bois
|area= PhytophthoraV1
|flux= Main
|étape= Exploration
|type= RBID
|clé= pubmed:32155921
|texte= Metabolomics to Exploit the Primed Immune System of Tomato Fruit.
}}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Main/Exploration/RBID.i -Sk "pubmed:32155921" \
| HfdSelect -Kh $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd \
| NlmPubMed2Wicri -a PhytophthoraV1
| This area was generated with Dilib version V0.6.38. |  |